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PURPOSE Conformal radiotherapy requires accurate patient positioning with reference to the initial three-dimensional (3D) CT image. Patient setup is controlled by comparison with portal images acquired immediately before patient treatment. Several automatic methods have been proposed, generally based on segmentation procedures. However, portal images are of(More)
Deformable registration is needed for a variety of tasks in establishing the voxel correspondence between respiratory phases. Most registration algorithms assume or imply that the deformation field is smooth and continuous everywhere. However, the lungs are contained within closed invaginated sacs called pleurae and are allowed to slide almost independently(More)
EMPIRE10 (Evaluation of Methods for Pulmonary Image REgistration 2010) is a public platform for fair and meaningful comparison of registration algorithms which are applied to a database of intrapatient thoracic CT image pairs. Evaluation of nonrigid registration techniques is a nontrivial task. This is compounded by the fact that researchers typically test(More)
PURPOSE We propose to simulate an artificial four-dimensional (4-D) CT image of the thorax during breathing. It is performed by deformable registration of two CT scans acquired at inhale and exhale breath-hold. MATERIALS AND METHODS Breath-hold images were acquired with the ABC (Active Breathing Coordinator) system. Dense deformable registrations were(More)
A main challenge in radiotherapy is to precisely take into account organs deformation and motion in order to adapt the treatment to each patient. This is particularly important in lung cancer where breathing leads to large displacements. In this work, breath holding techniques (with Active Breath Control device) were used to reduce movements during(More)
PURPOSE To study the interfraction reproducibility of breath-holding using active breath control (ABC), and to develop computerized tools to evaluate three-dimensional (3D) intrathoracic motion in each patient. METHODS AND MATERIALS Since June 2002, 11 patients with non-small-cell lung cancer enrolled in a Phase II trial have undergone four CT scans: one(More)
Motion estimation is an important issue in radiation therapy of moving organs. In particular, motion estimates from 4-D imaging can be used to compute the distribution of an absorbed dose during the therapeutic irradiation. We propose a strategy and criteria incorporating spatiotemporal information to evaluate the accuracy of model-based methods capturing(More)
Current methods of four-dimensional (4D) CT imaging of the thorax synchronise the acquisition with a respiratory signal to restrospectively sort acquired data. The quality of the 4D images relies on an accurate description of the position of the thorax in the respiratory cycle by the respiratory signal. Most of the methods used an external device for(More)
The EGEE grid offers the necessary infrastructure and resources for reducing the running time of particle tracking Monte-Carlo applications like GATE. However, efforts are required to achieve reliable and efficient execution and to provide execution frameworks to end-users. This paper presents results obtained with porting the GATE software on the EGEE(More)