David Rigby

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U.S. patent and citation data are used to measure technological relatedness between major patent classes in the USPTO. The technological relatedness measures, constructed as the probability that a patent in class j will cite a patent in class i, form the links of a knowledge network. Changes in this knowledge network are examined from 1975 to 2005.(More)
In a previous study, Keith (1983) showed by sequential gel electrophoresis of the esterase-5 protein in Drosophila pseudoobscura that a highly polymorphic locus with many alleles can have very similar frequency distributions in populations separated by 500 km. The present work studies another highly polymorphic locus, xanthine dehydrogenase, in the same(More)
Since its founding, NASA has been dedicated to the advancement of aeronautics and space science. The NASA Scientific and Technical Information (STI) Program Office plays a key part in helping NASA maintain this important role. The NASA STI Program Office is operated by Langley Research Center, the Lead Center for NASA's scientific and technical information.(More)
Production of events with hadronic and leptonic final states has been measured in e + e − collisions at centre-of-mass energies of 130–172 GeV, using the OPAL detector at LEP. Cross-sections and leptonic forward-backward asymmetries are presented, both including and excluding the dominant production of radiative Zγ events, and compared to Standard Model(More)
The host lymphatic network represents an important conduit for pathogen dissemination. Indeed, the lethal human pathogen group A streptococcus has a predilection to induce pathology in the lymphatic system and draining lymph nodes, however the underlying basis and subsequent consequences for disease outcome are currently unknown. Here we report that the(More)
To establish force-field-based (molecular) modeling capability that will accurately predict condensed-phase thermophysical properties for materials containing aliphatic azide chains, potential parameters for atom types unique to such chains have been developed and added to the COMPASS force field. The development effort identified the need to define four(More)
Asymptomatic carriage of gastrointestinal zoonoses is more common in people whose profession involves them working directly with domesticated animals. Subclinical infections (defined as an infection in which symptoms are either asymptomatic or sufficiently mild to escape diagnosis) are important within a community as unknowing (asymptomatic) carriers of(More)
It is clear that technology is a key driver of economic growth. Much less clear is where new technologies are produced and how the geography of U.S. invention has changed over the last two hundred years. Patent data report the geography, history, and technological characteristics of invention. However, those data have only recently become available in(More)
Cross-sections for hadronic and leptonic two-fermion events, and leptonic forward-backward asymmetries, have been measured in e + e ? collisions at a centre-of-mass energy of 161 GeV, using the OPAL detector at LEP. Results are presented both including and excluding the dominant production of radiative Z 0 events. We have measured R b , the ratio of the(More)