David Ray Mott

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A new microfluidic mixer is presented consisting of a rectangular channel with grooves placed in the top and bottom. This not only increases the driving force behind the lateral flow, but allows for the formation of advection patterns that cannot be created with structures on the bottom alone. Chevrons, pointing in opposite directions on the top and bottom,(More)
<lb>NEW QUASI-STEADY-STATE AND PARTIAL-EQUILIBRIUM METHODS<lb>FOR INTEGRATING CHEMICALLY REACTING SYSTEMS<lb>by<lb>David Ray Mott<lb>Chairperson: Bram van Leer<lb>We present new quasi-steady-state (QSS) and partial-equilibrium (PE) methods<lb>for integrating systems of ordinary di erential equations (ODEs) that arise from<lb>chemical reactions. These(More)
A mixer, based on the Dean vortex, is fabricated and tested in an on-chip format. When fluid is directed around a curve under pressure driven flow, the high velocity streams in the center of the channel experience a greater centripetal force and so are deflected outward. This creates a pair of counter-rotating vortices moving fluid toward the inner wall at(More)
A computational "toolbox" for the a priori design of optimized microfluidic components is presented. These components consist of a microchannel under low-Reynolds number, pressure-driven flow, with an arrangement of grooves cut into the top and bottom to generate a tailored cross-channel flow. An advection map for each feature (i.e., groove of a particular(More)
While the physics behind laminar flows has been studied for 200 years, understanding of how to use parallel flows to augment the capabilities of microfluidic systems has been a subject of study primarily over the last decade. The use of one flow to focus another within a microfluidic channel has graduated from a two-dimensional to a three-dimensional(More)
The Toolbox approach to the automated design of microfluidic components is extended to include a genetic algorithm search of candidate designs. Performance metrics for characterizing surface delivery are described, and the software is applied to choose sequences of grooves to add to a rectangular microchannel in order to optimize surface delivery for(More)
A simple design capable of 2-dimensional hydrodynamic focusing is proposed and successfully demonstrated. In the past, most microfluidic sheath flow systems have often only confined the sample solution on the sides, leaving the top and bottom of the sample stream in contact with the floor and ceiling of the channel. While relatively simple to build, these(More)
Technical note: application of α-QSS to the numerical integration of kinetic equations in tropospheric chemistry F. Liu, E. Schaller, and D. R. Mott Department of Environmental Meteorology, BTU Cottbus, Germany Laboratory for Computational Physics and Fluid Dynamics, Naval Research Laboratory, Washington, DC 20375-5320, USA Received: 9 May 2005 – Accepted:(More)
A study is presented that examines the effect of microfluidic mixing elements on direct and sandwich assays performed in microchannels. Patterned grooves were embossed in the top of microchannels made in PDMS using soft lithography. The grooves redirected the fluid flowing in the channel, enhancing delivery of the target from the bulk fluid to the surface(More)
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