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- David R. Bickel
- Biometrics
- 2011

In a novel approach to the multiple testing problem, Efron (2004, Journal of the American Statistical Association 99, 96-104; 2007a Journal of the American Statistical Association 102, 93-103; 2007b,â€¦ (More)

- David R. Bickel
- Bioinformatics
- 2003

MOTIVATION
The success of each method of cluster analysis depends on how well its underlying model describes the patterns of expression. Outlier-resistant and distribution-insensitive clustering ofâ€¦ (More)

- David R. Bickel
- Statistical applications in genetics andâ€¦
- 2013

Multiple comparison procedures that control a family-wise error rate or false discovery rate provide an achieved error rate as the adjusted p-value or q-value for each hypothesis tested. However,â€¦ (More)

- Mei Guo, Sean Yang, +4 authors Oscar S (Howie) Smith
- Plant Molecular Biology
- 2008

Allelic differences in expression are important genetic factors contributing to quantitative trait variation in various organisms. However, the extent of genome-wide allele-specific expression byâ€¦ (More)

- David R. Bickel
- Bioinformatics
- 2005

MOTIVATION
The reconstruction of gene networks from gene-expression microarrays is gaining popularity as methods improve and as more data become available. The reliability of such networks could beâ€¦ (More)

- David R. Bickel, Rudolf FrÃ¼hwirth
- Computational Statistics & Data Analysis
- 2006

- David R. Bickel
- 2010

For frequentist settings in which parameter randomness represents variability rather than uncertainty, the ideal measure of the support for one hypothesis over another is the difference in theâ€¦ (More)

- David R. Bickel
- 2011

The normalized maximum likelihood (NML) is a recent penalized likelihood that has properties that justify de ning the amount of discrimination information (DI) in the data supporting an alternativeâ€¦ (More)

- David R. Bickel
- Statistical applications in genetics andâ€¦
- 2008

The level of differential gene expression may be defined as a fold change, a frequency of upregulation, or some other measure of the degree or extent of a difference in expression across groups ofâ€¦ (More)

- Corey M. Yanofsky, David R. Bickel
- BMC Bioinformatics
- 2009

Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorithms, each justified by theory,â€¦ (More)