David R. Wright

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We have examined 365 versions of Linux. For every version, we counted the number of instances of common (global) coupling between each of the 17 kernel modules and all the other modules in that version of Linux. We found that the number of instances of common coupling grows exponentially with version number. This result is significant at the 99.99% level,(More)
BACKGROUND Dexmedetomidine, a highly selective alpha2-adrenoceptor agonist used for short-term sedation of mechanically ventilated patients, has minimal effect on ventilation. METHODS This study compared the respiratory effect of dexmedetomidine to that of remifentanil. The authors measured and compared respiratory responses of six healthy male volunteers(More)
UNLABELLED BRIEF SUMMARY: We describe the use of adenosine-induced cardiac arrest to facilitate intracranial aneurysm clip ligation. BACKGROUND Cerebral aneurysms are highly variable which may result in difficult surgical exposure for clip ligation in select cases. Secure clip placement is often not feasible without temporarily decompressing the aneurysm.(More)
The increase in maintenance of software and the increased amounts of reuse are having major positive impacts on the quality of software, but are also introducing some rather subtle negative impacts on the quality. Instead of talking about existing problems (faults), developers now discuss “potential problems,” that is, aspects of the program that do not(More)
BACKGROUND Transient adenosine-induced asystole is a reliable method for producing a short period of relative hypotension during surgical and endovascular procedures. Although the technique has been described in the endovascular treatment of brain arteriovenous malformations, aortic aneurysms, and posterior circulation cerebral aneurysms, little description(More)
PURPOSE OF REVIEW To present current knowledge about the metabolic management of patients undergoing solid organ transplantation, and potential organ donors. RECENT FINDINGS Appropriate management of electrolytes and glucose improves outcome after transplantation, although conflicting evidence exists. Patients with cirrhosis-induced hyponatremia can be(More)
BACKGROUND Dexmedetomidine is a highly selective alpha2-adrenoceptor agonist used for short-term sedation of mechanically ventilated patients. The analgesic profile of dexmedetomidine has not been fully characterized in humans. METHODS This study was designed to compare the analgesic responses of six healthy male volunteers during stepwise(More)
PURPOSE Excessive blood sampling, with its inherent risks, is of growing concern among clinicians. We performed this study to measure the changes in hematocrit (Hct) during a laboratory investigation where multiple blood samples are collected. The performance of a simple mathematical model, used in clinical practice to predict Hct changes, is evaluated. (More)
OBJECTIVE Neurophysiological intraoperative monitoring of the glossopharyngeal nerve has been performed only with needle electrodes inserted into the pharyngeal muscles or soft palate. We describe a noninvasive method of monitoring this cranial nerve. METHODS A 30-year-old man who presented with headache, as well as speech and swallowing difficulty,(More)