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Basement Membrane Sliding and Targeted Adhesion Remodels Tissue Boundaries During Uterine-vulval Attachment in C. elegans
Large gaps in basement membrane occur at sites of cell invasion and tissue remodelling in development and cancer. Though never followed directly in vivo, basement membrane dissolution or reducedExpand
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A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation
Invadopodia are specialized membrane protrusions composed of F-actin, actin regulators, signaling proteins, and a dynamically trafficked invadopodial membrane that drive cell invasion throughExpand
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Cell Division and Targeted Cell Cycle Arrest Opens and Stabilizes Basement Membrane Gaps
Large gaps in basement membrane (BM) occur during organ remodeling and cancer cell invasion. Whether dividing cells, which temporarily reduce their attachment to BM, influence these breaches isExpand
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SPARC promotes cell invasion in vivo by decreasing type IV collagen levels in the basement membrane
Overexpression of SPARC, a collagen-binding glycoprotein, is strongly associated with tumor invasion through extracellular matrix in many aggressive cancers. SPARC regulates numerous cellularExpand
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Ectopic Germ Cells Can Induce Niche-like Enwrapment by Neighboring Body Wall Muscle
Niche cell enwrapment of stem cells and their differentiating progeny is common and provides a specialized signaling and protective environment. Elucidating the mechanisms underlying enwrapmentExpand
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SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane
Overexpression of SPARC, a collagen-binding glycoprotein, is strongly associated with tumor invasion through extracellular matrix in many aggressive cancers. SPARC regulates numerous cellularExpand
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RETRACTED: Gene expression markers for Caenorhabditiselegans vulval cells
The analysis of cell fate patterning during the vulval development of Caenorhabditis elegans has relied mostly on the direct observation of cell divisions and cell movements (cell lineage analysis).Expand
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Invading, Leading and Navigating Cells in Caenorhabditis elegans: Insights into Cell Movement in Vivo
Highly regulated cell migration events are crucial during animal tissue formation and the trafficking of cells to sites of infection and injury. Misregulation of cell movement underlies numerousExpand
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α-Integrins dictate distinct modes of type IV collagen recruitment to basement membranes
Precise levels of collagen IV dictate the mechanical and signaling functions of basement membranes (BMs), but how collagen is incorporated into BMs in vivo is unclear. Jayadev et al. identifyExpand
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