BACKGROUND Bivalirudin, with selective use of glycoprotein (GP) IIb/IIIa inhibitor agents, is an accepted standard of care in primary percutaneous coronary intervention (PPCI). We aimed to compare antithrombotic therapy with bivalirudin or unfractionated heparin during this procedure. METHODS In our open-label, randomised controlled trial, we enrolled… (More)
BACKGROUND Aim of this trial was to compare rotational atherectomy followed by balloon angioplasty (rotablation [ROTA] group) with balloon angioplasty (percutaneous transluminal coronary angioplasty [PTCA] group) alone in patients with diffuse in-stent restenosis. METHODS AND RESULTS The ARTIST study is a multicenter, randomized, prospective European… (More)
We describe direct and quantitative evidence of free-radical production in the early stage after recanalisation in a patient undergoing primary coronary angioplasty for acute myocardial infarction. After successful initial dilation, the procedure was complicated by re-occlusion of the artery at the same site, with subsequent fall in free-radical generation.… (More)
During attempted removal of an infected permanent pacemaker system, the electrode fractured, leaving the tined tip embedded in the wall of the left subclavian vein. The electrode tip was successfully removed using a Dotter basket retrieval kit.
Addendum Since this report was first prepared a further 175 cases of clinically definite first stroke have been registered. None of the patients had non-stroke lesions detected by CT or found at necropsy. The frequency of non-stroke lesions in patients with a clinically definite first stroke is therefore five out of 498 (1 0). To establish diagnosis:… (More)
A 57 year old man required emergency coronary artery bypass surgery after dissection of the left main coronary artery during percutaneous transluminal coronary angioplasty. His symptoms recurred when the vein grafts became occluded. A dilatation device with the lowest profile was used to reduce the need for firm support from the guiding catheter during… (More)