David R. M. Lindsell

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The serum acute phase reactants, C-reactive protein (CRP) and orosomucoid, rose significantly within 24 to 48 hours of presentation in infants with definite necrotizing enterocolitis (NEC) compared with the levels in infants with symptoms who tolerated early reintroduction of enteral feeds. A serum CRP value greater than 10 mg/l within 48 hours identified(More)
In order to establish the normal range of values of Pulsatility (PI) and Resistance (RI) Indices in the intrarenal vasculature, a study of 50 healthy volunteers (23 males, 27 females), divided into five groups of 10 according to age, was performed with Duplex Doppler ultrasound. Both kidneys were examined in all individuals and, in 12, indices were also(More)
Ovarian function in post-menarchal girls with Type 1 diabetes was evaluated. Menstrual histories from 24 adolescents with Type 1 diabetes were compared with those from 24 age and sex matched controls. A fasting blood sample was obtained from subjects with Type 1 diabetes for the measurement of ovarian and adrenal sex hormones, LH and FSH, glucose and(More)
OBJECTIVE To evaluate transvaginal and transabdominal ultrasound scanning, with or without Doppler, as a diagnostic test for the accurate diagnosis of pelvic endometriosis. METHODS The MEDLINE (1966-2001) and EMBASE (1980-2001) databases were searched for relevant studies, published in English. Only studies fulfilling predefined criteria were selected. An(More)
Background. The postnatal imaging of infants with antenatally detected mild hydronephrosis remains controversial. Objective. Our aim was to establish the role and timing of micturating cystourethrography (MCUG) in mild hydronephrosis. Materials and methods. We performed a retrospective study of 61 infants (122 kidneys) referred with an antenatal diagnosis(More)
BACKGROUND The purpose of this study was to examine the relationship between glomerular filtration rate (GFR) measured at 5 years' diabetes duration and annual urine albumin excretion in a prospective cohort of children with type 1 diabetes (T1DM). METHODS Three hundred and eight children were followed from diagnosis of T1DM [aged 9.8 years (range(More)
To determine first, the accuracy of a gynaecological ultrasound service in the detection of four clinically significant pathologies, namely, uterine body malignancy, ovarian malignancy, ovarian dermoid cysts and other benign ovarian pathologies and second, to review the ultrasound imaging appearances of ovarian masses with histopathological correlation.(More)
In a prospective study 152 consecutive patients presenting with acute abdominal pain were assessed clinically and an ultrasonographic examination was performed immediately. Of these, 16 (11 per cent) patients would normally have had an immediate ultrasonographic scan requested; routine (within 24 h of admission) ultrasonographic examination would have been(More)