David R. Jacobs

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Coronary heart disease (CHD) is a major cause of death worldwide. In the U.S. CHD is responsible for approximated 1 in every 6 deaths with a coronary event occurring every 25 seconds and about 1 death every minute based on data current to 2007. Although a multitude of cardiovascular risks factors have been identified, CHD actually reflects complex(More)
Cumulating evidence from epidemiologic studies implicates cardiovascular health and cerebrovascular function in several brain diseases in late life. We examined vascular risk factors with respect to a cerebrovascular measure of brain functioning in subjects in mid-life, which could represent a marker of brain changes in later life. Breath-hold functional(More)
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