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OBJECTIVE To compare temporal aspects of peripheral neural responses and central auditory perception between groups of younger adult and elderly cochlear implant users. STUDY DESIGN Cohort study. SETTING Academic hospital and cochlear implant center. PATIENTS Adult cochlear implant users aged 28 to 57 years in the younger group (n = 5) and 61 to 89(More)
Recent advances in cochlear implant technology have focused renewed attention on the preservation of residual hearing. The focus on preservation of residual hearing is driven by the concept of electroacoustic stimulation. This option depends on the insertion of a short cochlear implant electrode into the basal region of the cochlea while preserving native(More)
OBJECTIVES/HYPOTHESIS The objectives were to evaluate the clinical relevance of traditional temporal bone radiographic descriptors and to investigate the efficacy of an alternative fracture classification scheme. STUDY DESIGN Retrospective consecutive case series. METHODS Charts and computed tomography scans representing 155 temporal bone fractures at a(More)
The cochlear nucleus is the first central pathway involved in the processing of peripheral auditory activity. The anterior ventral cochlear nucleus (AVCN), posterior ventral cochlear nucleus (PVCN) and dorsal cochlear nucleus (DCN) each contain predominant populations of neurons that have been well characterized regarding their morphological and(More)
The Golgi silver-impregnation method established itself as an important technique for distinguishing morphology at the individual neuron level. This technique has been especially useful for studying human neuroanatomy because it works on postmortem tissue but it is also unreliable and capricious. In this report, we describe a simple technique that was(More)
OBJECTIVES The study objectives were to compare the rate of neural recovery and speech perception performance in children with auditory neuropathy spectrum disorder (ANSD) and children with sensorineural hearing loss (SNHL) from other etiologies. STUDY DESIGN Cohort study. SETTING Academic hospital and cochlear implant center. SUBJECTS AND METHODS Ten(More)
Potassium channels play a critical role in defining the electrophysiological properties accounting for the unique response patterns of auditory neurons. Serial analysis of gene expression (SAGE), microarrays, RT-PCR, and real-time RT-PCR were used to generate a broad profile of potassium channel expression in the rat cochlear nucleus. This study identified(More)
OBJECTIVES To evaluate the natural history of traumatic conductive hearing loss. STUDY DESIGN Retrospective chart review. METHODS Otologic and audiometric evaluations of patients in the early posttraumatic phase were compared with evaluations at follow-up. Assessment included etiologies of trauma, classification of hearing loss, factors causing(More)
OBJECTIVES To determine the prevalence of cochlear implant electrode failure and the relationship with overall device failure. METHODS Electrode status was analyzed in 322 functioning and in-use devices from 366 adult cochlear implant patients currently followed at our center. An additional 21 devices that had been explanted were also analyzed. Electrode(More)
OBJECTIVES To investigate the feasibility and safety of an implantable epidural cortical stimulator for the treatment of severe tinnitus. STUDY DESIGN Prospective, controlled, single-blinded study of cortical stimulation for 4 weeks, and then an open-label stimulation period. SETTING Tertiary care referral center. PATIENTS Adults (n = 8) with constant(More)