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- Raúl López-Arnau, José Martínez-Clemente, David Pubill, E Escubedo, Jorge Camarasa
- British journal of pharmacology
- 2012
BACKGROUND AND PURPOSE
Here, we have compared the neurochemical profile of three new cathinones, butylone, mephedrone and methylone, in terms of their potential to inhibit plasmalemmal and vesicular… (More)
Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity
- David Pubill, Anna Maria Canudas, Mercè Pallàs, Antoni Camins, Jorge Camarasa, E Escubedo
- Naunyn-Schmiedeberg's Archives of Pharmacology
- 2003
The consequences of the neurotoxic insult induced by 3,4-methylenedioxymethamphetamine (MDMA, an amphetamine derivative with specific action on the serotonergic system) were compared with those of… (More)
- José Martínez-Clemente, Raúl López-Arnau, Sónia Abad, David Pubill, E Escubedo, Jorge Camarasa
- PloS one
- 2014
Mephedrone is a drug of abuse marketed as 'bath salts". There are discrepancies concerning its long-term effects. We have investigated the neurotoxicity of mephedrone in mice following different… (More)
- Judith Novellas, Raúl López-Arnau, Marcel li Carbó, David Pubill, Jorge Camarasa, E Escubedo
- Journal of psychopharmacology
- 2015
3,4-methylenedioxypyrovalerone or MDPV is a synthetic cathinone with psychostimulant properties more potent than cocaine. We quantified this drug in the striatum after subcutaneous administration to… (More)
- E Escubedo, Laura Guitart, +5 authors Jordi Camarasa
- Brain Research
- 1998
Chronic administration of methamphetamine to rats induces neurotoxicity characterized by a loss of striatal dopaminergic terminals and reactive gliosis. Subcutaneous administration of methamphetamine… (More)
- Raúl López-Arnau, José Martínez-Clemente, Marcel·lí Carbó, David Pubill, Jorge Camarasa
- Progress in Neuro-Psychopharmacology and…
- 2013
INTRODUCTION
Methylone (3,4-methylenedioxymethcathinone) is a new psychoactive substance and an active ingredient of "legal highs" or "bath salts". We studied the pharmacokinetics and locomotor… (More)
- José Martínez-Clemente, Raúl López-Arnau, Marcel·lí Carbó, David Pubill, Jordi Camarasa, E Escubedo
- Psychopharmacology
- 2013
Mephedrone (4-methylmethcathinone) is a still poorly known drug of abuse, alternative to ecstasy or cocaine. The major aims were to investigate the pharmacokinetics and locomotor activity of… (More)
- Sara García-Ratés, Jordi Camarasa, Ana I Sánchez-García, Luis M. Gandia, E Escubedo, David Pubill
- Toxicology and applied pharmacology
- 2010
Previous work by our group demonstrated that homomeric alpha7 nicotinic acetylcholine receptors (nAChR) play a role in the neurotoxicity induced by 3,4-methylenedioxymethamphetamine (MDMA), as well… (More)
- José Martínez-Clemente, E Escubedo, David Pubill, Jorge Camarasa
- European Neuropsychopharmacology
- 2012
INTRODUCTION
We described a first approach to the pharmacological targets of mephedrone (4-methyl-methcathinone) in rats to establish the basis of the mechanism of action of this drug of abuse.
… (More)
- David Pubill, Carlos Chipana, Antoni Camins, Mercè Pallàs, Jordi Camarasa, E Escubedo
- Toxicology and applied pharmacology
- 2005
The pro-oxidative effect of methamphetamine (METH) in dopamine terminals was studied in rat striatal synaptosomes. Flow cytometry analysis showed increased production of reactive oxygen species (ROS)… (More)