Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications.
Alzheimer's disease (AD) is characterized pathologically by the abundance of senile plaques and neurofibrillary tangles in the brain. We synthesized over 1200 novel gamma-secretase modulator (GSM)… (More)
Abstract 1-Methyl, 1-(alkoxymethyl) and 1-(trimethylsilylmethyl)benzotriazoles are metallated at the α-carbon. Trapping of the resulting metallated species with chlorotrimethylsilane gives compounds… (More)
Repeated metallation/silylation of 1-methoxymethylbenzotriazole 1 gives a high yield of the 4-tristrimethylsilyl benzotriazole derivative 5 which undergoes a high yielding fluoride-catalysed Peterson… (More)