David P. McMullen

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OBJECTIVE We used native sensorimotor representations of fingers in a brain-machine interface (BMI) to achieve immediate online control of individual prosthetic fingers. APPROACH Using high gamma responses recorded with a high-density electrocorticography (ECoG) array, we rapidly mapped the functional anatomy of cued finger movements. We used these(More)
To increase the ability of brain-machine interfaces (BMIs) to control advanced prostheses such as the modular prosthetic limb (MPL), we are developing a novel system: the Hybrid Augmented Reality Multimodal Operation Neural Integration Environment (HARMONIE). This system utilizes hybrid input, supervisory control, and intelligent robotics to allow users to(More)
Deep brain stimulation is an effective and safe treatment option for a variety of medical conditions including Parkinson’s disease and essential tremor, and carries a Humanitarian Device Exemption from the FDA for the treatment of dystonia and obsessive compulsive disorder. Recent work has demonstrated the possibility of utilizing deep brain stimulation of(More)
Intracranial electroencephalographic (iEEG) signals from two human subjects were used to achieve simultaneous neural control of reaching and grasping movements with the Johns Hopkins University Applied Physics Lab (JHU/APL) Modular Prosthetic Limb (MPL), a dexterous robotic prosthetic arm. We performed functional mapping of high gamma activity while the(More)
Language tasks require the coordinated activation of multiple subnetworks-groups of related cortical interactions involved in specific components of task processing. Although electrocorticography (ECoG) has sufficient temporal and spatial resolution to capture the dynamics of event-related interactions between cortical sites, it is difficult to decompose(More)
Effective user control of highly dexterous and robotic assistive devices requires intuitive and natural modalities. Although surgically implanted brain-computer interfaces (BCIs) strive to achieve this, a number of non-invasive engineering solutions may provide a quicker path to patient use by eliminating surgical implantation. We present the development of(More)
We present DiVE into Alcohol, a virtual reality (VR) program that can be used in chemistry education at the high school and college level, both as an immersive experience, or as a web-based program. The program is presented in the context of an engaging topic--the oxidation of alcohol based on genetic differences in metabolism within the liver cell. The(More)
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