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Patient-reported outcome and satisfaction scores have become increasingly important in evaluating successful surgery. This case-matched control study compared patient-reported outcome and satisfaction data following hip resurfacing and total hip arthroplasty. Thirty-three consecutive patients selected for hip resurfacing were compared with 99 patients(More)
Atherosclerotic coronary artery disease is a progressive process for which effective palliative methods have been developed. The evolution of surgical bypass grafting over the past two decades now permits its application to most symptomatic patients. In 1977 an alternative, transluminal angioplasty, was first performed in man and has become widely accepted.(More)
BACKGROUND Fresh-frozen plasma (FFP) is widely used in critically ill patients, despite a weak evidence base. Factors that influence the decision to transfuse FFP before intravascular catheter insertion are poorly described. METHODS We undertook a case-controlled study based on a prospective cohort study of 1923 admissions to 29 intensive care units in(More)
Endothelium-derived hyperpolarising factor (EDHF) causes vasorelaxation and may contribute to the release of the endogenous fibrinolytic factor, tissue-plasminogen activator (t-PA). Rotigaptide enhances communication via the connexin 43 gap junction subunit and may potentiate the vascular actions of EDHF. The aims of the present study were therefore to(More)