David O. Rodríguez

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PURPOSE Hypersensitivity to fungi is associated with rhinoconjunctivitis and asthma. For some fungi, such as Alternaria alternata (A. alternata), the symptoms of asthma are persistent, increasing disease severity and the risk of fatal outcomes. There are a large number of species of fungi but knowledge of them remains limited. This, together with the(More)
This paper presents a brief description of the protein side chain packing problem (PSCPP) and a performance assessment, on this problem, of three state-of-the-art algorithms: SCWRL4, OPUS-Rota, and CIS-RR. In order to perform a fair comparison, the algorithms are evaluated on three data sets, two of them were previously proposed in the literature and a set(More)
BACKGROUND Despite the evidence that Lactoferrin (Lf) is involved in allergic asthma processes, it is unknown whether neutrophils can be one of the main cellular sources of this key inflammatory mediator directly in response of an IgE mediated stimulus. The present study was undertaken to analyze this question. METHODS Neutrophils from healthy subjects (n(More)
—The development of new technologies for the design of DNA microarrays has boosted the generation of large volumes of biological data, which requires the development of efficient computational methods for their analysis and annotation. On these sets of data, the biclusters construction algorithms attempt to identify coherent associations of genes and(More)
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