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This paper is based on the results of research carried out during the first year and a half of the Understandings of Consequence Project. We are continuing to research and develop the ideas presented here. If you have feedback for us or would like to keep in touch with developments on the project, please check our website atPrincipal Investigators. Any(More)
Normalisation of data to minimise the impact of technical variation on comparative sample analysis is often carried out. Using SELDI data as a model, we have examined the effects of normalisation by TIC which is commonly used for MS data. Significant intergroup differences in normalisation factor were found for serum profiles which could not be explained by(More)
This paper is based on the results of research carried out during the first year of the Understandings of Consequence Project. We are continuing to research and develop the ideas presented here. If you have feedback for us or would like to keep in touch with developments on the project, please check our website at Any opinions, findings, conclusions or(More)
Student lawyers are among the most intelligent of students in the psychometric sense. They are able dedicated learners who have passed the hurdles of earlier education with excellent records. Moreover, good reasoning in terms of claims and evidence is central to their enterprise. Lawyers—student or professional—need to consider not only the side of the case(More)
BACKGROUND Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue for biomarker discovery. Such experiments are often conducted using MALDI-TOF (matrix-assisted laser desorption/ionisation time-of-flight) and SELDI-TOF (surface-enhanced laser(More)
This paper is based on the results of research carried out during the first year of the Understandings of Consequence Project. We are continuing to research and develop the ideas presented here. If you have feedback for us or would like to keep in touch with developments on the project, please check our website at Any opinions, findings, conclusions or(More)
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