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This paper was written as part of a project funded by the John D. and Catherine T. MacArthur Foundation. The authors thank the foundation for its help, adding the standard disclaimer that the ideas expressed here do not necessarily reflect the position or policy of supporting agencies. We also thank Carlos Vasco for working through a number of the concepts(More)
Plans and situated actions: The problem of human-machine interaction Lucy Suchman Situated learning: Legitimate peripheral participation Jean Lave and Etienne Wenger Street mathematics and school mathematics Library of Congress Cataloging-in-Publifation Data Distributed cognitions : psychological and educational considerations / edited by Gavriel Salomon,(More)
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This paper is based on the results of research carried out during the first year and a half of the Understandings of Consequence Project. We are continuing to research and develop the ideas presented here. If you have feedback for us or would like to keep in touch with developments on the project, please check our website atPrincipal Investigators. Any(More)
Normalisation of data to minimise the impact of technical variation on comparative sample analysis is often carried out. Using SELDI data as a model, we have examined the effects of normalisation by TIC which is commonly used for MS data. Significant intergroup differences in normalisation factor were found for serum profiles which could not be explained by(More)
Both the meaning and the challenge of``transfer of learning'' are well-expressed in a story told to one of us by a disappointed professor of physics at a nearby college. Among the stock problems explored in the physics course was one like this: ``A ball weighing three kilograms is dropped from the top of a hundred meter tower. How many seconds does it take(More)
The ability to discriminate whether pictured box shapes (parallelopipeds) are projections of three-dimensional rectangular forms has been demonstrated by Perkins and Cooper in US populations and interpreted as a symptom of a general Gestalt strategy in perception. Deregowski suggested earlier that this perceptual strategy might not appear as strongly in(More)
BACKGROUND Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue for biomarker discovery. Such experiments are often conducted using MALDI-TOF (matrix-assisted laser desorption/ionisation time-of-flight) and SELDI-TOF (surface-enhanced laser(More)