David Morrissey

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We study the influence of boundary conditions on stationary, periodic patterns in one-dimensional systems. We show how a conceptual understanding of the structure of equilibria in large domains can be based on the characterization of boundary layers through displacement-strain curves. Most prominently, we distinguish wavenumber-selecting and phase-selecting(More)
The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly suppress phenotypes of let-7 family microRNA mutants, a(More)
Efficient tissue-specific delivery is a crucial factor in the successful development of therapeutic oligonucleotides. Screening for novel delivery methods with unique tissue-homing properties requires a rapid, sensitive, flexible and unbiased technique able to visualize the in vivo biodistribution of these oligonucleotides. Here, we present whole body(More)
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