Learn More
BACKGROUND Azithromycin is a macrolide antibiotic with anti-inflammatory and immunomodulatory properties. We tested the hypothesis that azithromycin would decrease the frequency of exacerbations, increase lung function, and improve health-related quality of life in patients with non-cystic fibrosis bronchiectasis. METHODS We undertook a randomised,(More)
The goal of this study was to seek indirect evidence that smoking is an aetiological factor in some patients with non-specific interstitial pneumonia (NSIP). Ten current and eight ex-smokers with NSIP were compared to controls including 137 current smokers with no known interstitial lung disease and 11 non-smokers with NSIP. Prevalence and extent of(More)
BACKGROUND Chronic Obstructive Pulmonary Disease (COPD) is a progressive airway disease characterised by neutrophilic airway inflammation or bronchitis. Neutrophilic bronchitis is associated with both bacterial colonisation and lung function decline and is common in exacerbations of COPD. Despite current available therapies to control inflammation,(More)
Executive Summary In recent decades, the world has witnessed an array of harmful invasions by exotic marine and freshwater organisms. In 1998, the Washington State Department of Natural Resources organized a rapid survey of exotic organisms in Puget Sound in order to provide the public and policymakers with information on the status of exotic species in(More)
A 41-year-old man with no previous asbestos exposure presented with 6 months of dull right lower chest pain and weight loss. The initial computed tomography (CT) scan was reported as showing a soft tissue thickening in the posterior mediastinum with non-specific nodules in the horizontal and oblique fissures. An endoscopic ultrasound-guided fine needle(More)
BACKGROUND The term severe acute respiratory infection (SARI) encompasses a heterogeneous group of respiratory illnesses. Grading the severity of SARI is currently reliant on indirect disease severity measures such as respiratory and heart rate, and the need for oxygen or intensive care. With the lungs being the primary organ system involved in SARI, chest(More)
Track for modern ballasted high speed railway lines typically uses continuous welded rail with continuous ballast. Continuous ballast is often specified over features involving discontinuity of track support including structural movement or expansion joints found in long railway bridges. Accelerated degradation of track geometry has been observed at these(More)
Availability: Public (only once status above is "Accepted") The question whether marginal cost pricing should be applied in the transportation sector has attained a great deal of attention during the last few years. It is argued that marginal cost pricing, or marginal social cost pricing – a term used when one wishes to emphasise that the pricing is applied(More)
  • 1