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  • Heather K. MacAlpine, Raluca Gordân, Sara Kathleen Powell, Alexander J. Hartemink, David M. MacAlpine
  • Biology, Medicine
  • Genome research
  • 2010 (First Publication: 1 February 2010)
  • The origin recognition complex (ORC) is an essential DNA replication initiation factor conserved in all eukaryotes. In Saccharomyces cerevisiae, ORC binds to specific DNA elements; however, in higherContinue Reading
  • Daphne Georlette, Soyeon Ahn, +7 authors Michael R Botchan
  • Medicine, Biology
  • Genes & development
  • 2007 (First Publication: 15 November 2007)
  • Myb-MuvB (MMB)/dREAM is a nine-subunit complex first described in Drosophila as a repressor of transcription, dependent on E2F2 and the RBFs. Myb, an integral member of MMB, curiously plays no roleContinue Reading