David M. Reith

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BACKGROUND Early detection of acute tubular necrosis (ATN) could permit implementation of salvage therapies and improve patient outcomes in acute renal failure (ARF). The utility of single and combined measurements of urinary tubular enzymes in predicting ARF in critically ill patients has not been evaluated using the receiver-operating characteristic (ROC)(More)
BACKGROUND Prediction of suicide risk is difficult in clinical practice. AIMS To identify changes in clinical presentation predictive of suicide in patients treated for repeated episodes of self-poisoning. METHOD A nested case-control study used the Hunter Area Toxicology Service database to identify exposure variables and the National Death Index to(More)
OBJECTIVE To quantify the non-suicidal mortality subsequent to hospital treated self-poisoning, and to identify risk factors for non-suicidal death. METHOD A prospective longitudinal cohort design was used, with data-linkage between the Hunter Area Toxicology Service database and the National Death Index. All patients with deliberate self-poisoning for a(More)
BACKGROUND While there have been considerable advances in diabetes management, self-monitoring of blood glucose remains vital. A number of studies, predominantly in adults, have confirmed that logbook entries are prone to a number of common errors. To date, no studies in either adults or children have looked at the accuracy of verbally reported(More)
Intravenous acetaminophen is a commonly used analgesic following surgery. The aims of this study were to determine the population pharmacokinetic profile of intravenous acetaminophen and its metabolites in adult surgical patients and to identify patient characteristics associated with acetaminophen metabolism in the postoperative period. 53 patients were(More)
OBJECTIVE To analyze the risk factors for suicide, premature death and all-cause death in a representative population of hospital-treated deliberate self-poisoning patients. METHOD A prospective cohort study using data-linkage between the Hunter Area Toxicology Service Database and the National Death Index of the Australian Institute of Health and(More)
The objective of the study was to assess the use of a computer toxicology database/clinical decision aid by clinical practitioners. The study investigated the sources that Emergency Department (ED) personnel use to obtain toxicology information and performed a quality audit of the current database. A questionnaire survey of ED staff was used in departments(More)
BACKGROUND Polypharmacy and inappropriate continuation of medicines can lead to a significant risk of adverse drug events and drug interactions with patient harm and escalating health care costs as a result. Thorough review of patients' medications focusing on the need for each drug can reduce the potential for harm. Limitations in performing effective(More)
PURPOSE To identify poisons information resources most commonly utilized by Australasian Emergency Department staff, and examine attitudes regarding the benefits and user experience of the electronic products used. METHODS A survey tool was mailed to six Emergency Departments each in New Zealand and Australia to be answered by medical and nursing staff.(More)
INTRODUCTION The New Zealand National Poisons Centre has developed an extensive clinical poisons information database, TOXINZ. This resource was originally provided on a CD-Rom, and in 2002 made accessible solely via the Internet (www.toxinz.com). It was unknown whether users would prefer the CD-Rom or Internet version to access the same information. (More)
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