David M. Reith

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BACKGROUND Early detection of acute tubular necrosis (ATN) could permit implementation of salvage therapies and improve patient outcomes in acute renal failure (ARF). The utility of single and combined measurements of urinary tubular enzymes in predicting ARF in critically ill patients has not been evaluated using the receiver-operating characteristic (ROC)(More)
OBJECTIVES To examine risk factors associated with re-presentation (event rates) following an initial episode of hospital treated self-poisoning. METHOD A longitudinal cohort study using the Hunter Area Toxicology Service (HATS) database of all presentations to hospital of self-poisoned patients aged 10-19 in Newcastle and Lake Macquarie Regions of New(More)
BACKGROUND Prediction of suicide risk is difficult in clinical practice. AIMS To identify changes in clinical presentation predictive of suicide in patients treated for repeated episodes of self-poisoning. METHOD A nested case-control study used the Hunter Area Toxicology Service database to identify exposure variables and the National Death Index to(More)
OBJECTIVE To quantify the non-suicidal mortality subsequent to hospital treated self-poisoning, and to identify risk factors for non-suicidal death. METHOD A prospective longitudinal cohort design was used, with data-linkage between the Hunter Area Toxicology Service database and the National Death Index. All patients with deliberate self-poisoning for a(More)
BACKGROUND While there have been considerable advances in diabetes management, self-monitoring of blood glucose remains vital. A number of studies, predominantly in adults, have confirmed that logbook entries are prone to a number of common errors. To date, no studies in either adults or children have looked at the accuracy of verbally reported(More)
Intravenous acetaminophen is a commonly used analgesic following surgery. The aims of this study were to determine the population pharmacokinetic profile of intravenous acetaminophen and its metabolites in adult surgical patients and to identify patient characteristics associated with acetaminophen metabolism in the postoperative period. 53 patients were(More)
OBJECTIVE To analyze the risk factors for suicide, premature death and all-cause death in a representative population of hospital-treated deliberate self-poisoning patients. METHOD A prospective cohort study using data-linkage between the Hunter Area Toxicology Service Database and the National Death Index of the Australian Institute of Health and(More)
The objective of the study was to assess the use of a computer toxicology database/clinical decision aid by clinical practitioners. The study investigated the sources that Emergency Department (ED) personnel use to obtain toxicology information and performed a quality audit of the current database. A questionnaire survey of ED staff was used in departments(More)
BACKGROUND Knowing where and why harm occurs in general practice will assist patients, doctors, and others in making informed decisions about the risks and benefits of treatment options. Research to date has been unable to verify the safety of primary health care and epidemiological research about patient harms in general practice is now a top priority for(More)
BACKGROUND While there have been considerable advances in the medical management of type 1 diabetes mellitus (T1DM), for many, glycaemic control remains substandard. Nutrition and eating behaviour are important additional factors to consider with regards to T1DM management and outcomes. Intuitive eating is one such factor, and has not previously been(More)