David M. Collins

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OBJECTIVE To report the prescribing of antipsychotics to the youth population of the Canadian province of Manitoba during the course of a decade. METHODS Use of antipsychotics in children and adolescents (aged 18 years or younger) was described using data collected from the administrative health databases of Manitoba Health and the Statistics Canada(More)
OBJECTIVE This study evaluated the prescribing patterns and costs for antipsychotic agents in the population of the Canadian province of Manitoba over the past decade. METHODS A population-based study of antipsychotic utilization and costs was conducted on data collected from the administrative databases of the Manitoba Population Health Data Repository(More)
OBJECTIVE To report the findings of a switch from brand-name to generic clozapine in a Canadian outpatient population. METHOD The medical records of 58 outpatients diagnosed with schizophrenia and other psychotic disorders and stabilized on brand-name clozapine therapy were reviewed retrospectively. Patients were switched from brand-name to generic(More)
OBJECTIVE "Antibenzodiazepine" campaigns have been conducted worldwide to limit the prescribing of these drugs because of concerns about inappropriate use and addiction. The causal relationship between long-term use and escalation to high doses has not been proven. This study assessed the extent of dose escalation among individuals who were long-term users(More)
OBJECTIVE Generic drugs are less expensive than their branded equivalents, but receive limited promotion. This study sought to examine how user rates of individual selective serotonin reuptake inhibitors (SSRIs) changed after the introduction of their generic equivalents. METHOD Administrative health and census data were used to examine the rates of use(More)
The age-hardening behaviour and microstructure development of high strength Ni-based superalloys ABD-D2, D4, and D6 with varying Nb/Ti ratios have been studied. The studied alloys have large volume fractions and multimodal size distributions of the γ precipitates, making them sensitive to cooling conditions following solution heat treatment. Differential(More)
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