David Lowman

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PURPOSE The purpose of this study was to compare the effectiveness of 5% sodium hypochlorite (NaOCl) to that of ferric sulfate (FeSO4) as a pulpotomy medicament in decayed primary molars. METHODS Healthy subjects between 4 and 9 years with at least 2 primary molars needing pulpotomy consented to receive either NaOCl or FeSO4 and restoration with IRM(More)
BACKGROUND The use of Escherichia coli purine nucleoside phosphorylase (PNP) to activate fludarabine has demonstrated safety and antitumor activity during preclinical analysis and has been approved for clinical investigation. PATIENTS AND METHODS A first-in-human phase I clinical trial (NCT 01310179; IND 14271) was initiated to evaluate safety and(More)
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