David L McGlassen

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BACKGROUND The active metabolite of clopidogrel binds the P2Y12 ADP receptor on the platelet surface via a disulfide bond. N-Acetylcysteine (NAC) is able to reduce disulfide bonds. We postulated that NAC might reverse clopidogrel's effect on platelets. METHODS Two groups of patients were investigated. Group 1 included 11 patients with stable coronary(More)
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