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  • Juliana B. R. Corrêa Soares, Diego Menezes, +9 authors Marcus F. Oliveira
  • Medicine, Biology
  • PLoS neglected tropical diseases
  • 2009 (First Publication: 1 July 2009)
  • Background The parasitic trematode Schistosoma mansoni is one of the major causative agents of human schistosomiasis, which afflicts 200 million people worldwide. Praziquantel remains the main drugExpand
  • Samkele Nsumiwa, David Kuter, Sergio Wittlin, Kelly Chibale, Timothy J. Egan
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry
  • 2013 (First Publication: 1 July 2013)
  • In order to probe structure-activity relationships of association with ferriprotoporphyrin IX (logK) and inhibition of β-hematin formation, a series of 4-aminoquinolines with varying substituents atExpand
  • David Kuter, Gerhard A Venter, Kevin J. Naidoo, Timothy J. Egan
  • Chemistry, Medicine
  • Inorganic chemistry
  • 2012 (First Publication: 10 September 2012)
  • Speciation of ferriprotoporphyrin IX, Fe(III)PPIX, in aqueous solution is complex. Despite the use of its characteristic spectroscopic features for identification, the theoretical basis of the uniqueExpand