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RIG-I detects double-stranded RNA (dsRNA) to trigger antiviral cytokine production. Protein deamidation is emerging as a post-translational modification that chiefly regulates protein function. We report here that UL37 of herpes simplex virus 1 (HSV-1) is a protein deamidase that targets RIG-I to block RNA-induced activation. Mass spectrometry analysis(More)
Comments or questions regarding these guidelines are always welcome. The Department of Natural Resources intends to update this document on a regular basis as changes and improvements warrant. You can contact the Division of Water by the following means: • E-Mail your questions or comments to: water_inquiry@dnr.state.in.us • Send questions or comments to:(More)
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