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  • David K. Welsh, Diomedes E. Logothetis, Markus Meister, Steven M. Reppert
  • Medicine, Biology
  • Neuron
  • 1995 (First Publication: 1 April 1995)
  • Within the mammalian hypothalamus, the suprachiasmatic nucleus (SCN) contains a circadian clock for timing of diverse neuronal, endocrine, and behavioral rhythms. By culturing cells from neonatal ratContinue Reading
  • Andrew C Liu, Hien G. Tran, Eric Erquan Zhang, Aaron A. Priest, David K. Welsh, Steve A Kay
  • Biology, Medicine
  • PLoS genetics
  • 2008 (First Publication: 1 February 2008)
  • The mammalian circadian clockwork is composed of a core PER/CRY feedback loop and additional interlocking loops. In particular, the ROR/REV/Bmal1 loop, consisting of ROR activators and REV-ERBContinue Reading
  • David K. Welsh, Seung-Hee Yoo, Andrew C Liu, Joseph S. Takahashi, Steve A Kay
  • Medicine, Biology
  • Current Biology
  • 2004 (First Publication: 1 December 2004)
  • Circadian (ca. 24 hr) oscillations in expression of mammalian "clock genes" are found not only in the suprachiasmatic nucleus (SCN), the central circadian pacemaker, but also in peripheral tissues.Continue Reading
  • Louisa M Wang, Joanna M. Dragich, +4 authors Christopher S Colwell
  • Biology, Medicine
  • ASN neuro
  • 2009 (First Publication: 6 May 2009)
  • Genes responsible for generating circadian oscillations are expressed in a variety of brain regions not typically associated with circadian timing. The functions of this clock gene expression areContinue Reading