Learn More
Lipid metabolism is essential for growth and generates much of the energy needed during periods of starvation. In Drosophila, fasting larvae release large quantities of lipid from the fat body but it is unclear how and where this is processed. Here we identify the oenocyte as the principal cell type accumulating lipid droplets during starvation.(More)
Primary hepatocytes cultured in a medium supplemented with amino acids and lipogenic substrates responded to increased extracellular glucose by increasing the secretion of VLDL apoB. This effect was accompanied by an increased secretion of VLDL triacylglycerol (TAG) derived from endogenous stores. Glucose also stimulated intracellular TAG mobilization via(More)
Peroxisome proliferator-activated receptor alpha (PPAR alpha)-null mice were used to investigate the nature of the relationship between the normal circadian rhythm of hepatic PPAR alpha expression and the expression of the lipogenic and cholesterogenic sterol regulatory element-binding protein (SREBP)-regulated genes, acetyl-CoA carboxylase, fatty acid(More)
Since the 19th century to present day, stereotyping of Black male athletes has depicted them as athletically superior while intellectually inferior to White male athletes (Harrison & Lawrence, 2004). In this paper, the purpose is to theorize on the race-based stereotyping of Black male student-athletes at the collegiate level. Our comments are situated in(More)
Locke's view that continuants are numerically distinct from their constituting hunks of matter is popular enough to be called the " standard account ". 1 It was given its deenitive contemporary statement by David Wiggins in Sameness and Substance 2 , and has been defended by many since. Baker's interesting book contributes new arguments for this view, a new(More)
Roux-en-Y gastric bypass (RYGB) is a weight-reduction procedure resulting in rapid resolution of type 2 diabetes (T2D). The role of pancreatic islet function in this restoration of normoglycemia has not been fully elucidated. Using the diabetic Goto-Kakizaki (GK) rat model, we demonstrate that RYGB restores normal glucose regulation of glucagon and insulin(More)
  • 1