David K. Welch

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6 patients with radiolucent cholelithiasis underwent randomized successive 3-week trials on each of the following medications: beta-glycerophosphate, linoleic acid, or purified soybean lecithin. Bile-rich duodenal fluid was obtained prior to the study and following each treatment period. Soybean lecithin feeding effected a qualitative change in biliary(More)
Eicosatetraenyl (3-aminopropyl) phosphonate (URI-73A), an experimental anti-hypertensive drug, when tested in vitro, inhibits platelet aggregation especially that induced by arachidonic acid (AA) and to a lesser degree by epinephrine. Preincubation of human platelets with this compound in the majority of individuals resulted in a dose-dependent inhibition(More)
A majority of the individual molecular species of phosphatidic acid dimethyl esters derived from multispecies egg yolk and soybean phosphatidylcholines have been separated by reverse-phase high pressure liquid chromatography. Two Partisil-10 ODS columns connected in tandem and the eluents acetonitrile or methanol/water (95∶5) were used for molecular species(More)
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