David J Jenkinson

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INTRODUCTION Data on quality of life beyond 2 years after intensive care discharge are limited and we aimed to explore this area further. Our objective was to quantify quality of life and health utilities in the 5 years after intensive care discharge. METHODS A prospective longitudinal cohort study in a University Hospital in the UK. Quality of life was(More)
OBJECTIVES To test the hypothesis that nurse led follow-up programmes are effective and cost effective in improving quality of life after discharge from intensive care. DESIGN A pragmatic, non-blinded, multicentre, randomised controlled trial. SETTING Three UK hospitals (two teaching hospitals and one district general hospital). PARTICIPANTS 286(More)
OBJECTIVE To identify factors associated with intention to attend a hypothetical eye health test and provide an evidence base for developing an intervention to maximise attendance, for use in studies evaluating glaucoma screening programmes. DESIGN Theory-based cross-sectional survey, based on an extended Theory of Planned Behaviour (TPB) and the Common(More)
BACKGROUND To develop patient-reported outcome instruments, statistical techniques (e.g., principal components analysis; PCA) are used to examine correlations among items and identify interrelated item subsets (empirical factors). However, interpretation and labelling of empirical factors is a subjective process, lacking precision or conceptual basis. We(More)
INTRODUCTION We conducted a systematic review of evidence on the effectiveness of imatinib at escalated doses of 600 mg/day or 800 mg/day for treatment of adults with unresectable or metastatic gastrointestinal stromal tumours (GIST), following progression on imatinib at the 400 mg/day dose, compared with sunitinib and/or 'best supportive care'. METHODS(More)
OBJECTIVES To investigate whether intergroup contact in addition to education is more effective than education alone in reducing stigma of mental illness in adolescents. DESIGN A pragmatic cluster randomised controlled trial compared education alone with education plus contact. Blocking was used to randomly stratify classes within schools to condition.(More)
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