David J Ireland

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Benign paroxysmal positional vertigo (BPPV) is the commonest peripheral vestibular disorder seen in dizziness clinics. It was long believed that the condition was caused by inorganic particles in the cupula of the posterior semicircular canal (PSC). More recently it has been suggested that BPPV may result from free-floating densities in the endolymph of the(More)
The purpose of this study was to evaluate the effects of two exercise programs on balance performance in patients with chronic peripheral vestibular dysfunction and to assess whether these exercise programs induce adaptive modifications of the vestibulo-ocular reflex (VOR). Patients were randomly assigned to one of two groups. (1) Those in the Rehab (Reh)(More)
A pilot study was undertaken in our Vestibular Disorders Clinic to re-evaluate the clinical benefits of vestibular evoked myogenic potentials (VEMP). In seven normal subjects and 20 documented unilateral peripheral vestibular disorder patients, electromyograms were recorded from surface electrodes over the sternomastoid muscles and averaged in response to(More)
Events following the extinction of lights after 1-minute exposures of naive, normal subjects to an optokinetic stimulus at 40 deg/sec have been closely examined and quantified. Mean eye displacement in each slow phase decreased from 10.12 +/- 1.61 deg during optokinetic nystagmus (OKN) to 3.36 +/- 2.32 deg during optokinetic afternystagmus (OKAN).(More)
The dependence of human OKAN characteristics on optokinetic (OK) stimulus velocity was examined using the two-component double exponential model for OKAN decay. Drum velocities studied were between 10 degrees and 70 degrees deg/sec over a constant exposure period of 60 sec. Results reveal two distinct types of response: a 'low'-level response at lower drum(More)
The ocular tilt reaction leads to an alteration in the subjective visual vertical (SVV). Nonsurgical peripheral vestibular dysfunction only rarely leads to changes in the SVV. To our knowledge, no studies have examined the effects on the SVV in patients with benign positional paroxysmal vertigo (BPPV) post Hallpike and Semont maneuvers. Sixteen patients(More)
Characteristics of human vertical optokinetic nystagmus (VOKN) and afternystagmus (VOKAN) were examined by electro-oculography in 18 normal human subjects by means of the analysis of slow phase velocity (SPV) and area under the regression curve of the VOKAN decay. Under normal gravity, subjects were tested in upright and left ear down (90 degrees roll)(More)
Stimulus velocity dependence of human VOKN and VOKAN was investigated using 20 degrees, 40 degrees, 60 degrees, and 80 degrees/s optokinetic stimulation. In our experimental conditions, 40 degrees/s was found to be the most appropriate stimulus velocity for inducing reliable VOKN and VOKAN based on the analysis of SPV, gain, and the area under the VOKAN(More)
Normal human subjects were exposed to repeated optokinetic afternystagmus (OKAN) testing in either one direction or alternating directions of stripe movement. Sessions were conducted at intervals of either one week or several weeks. Repeated exposure to OKAN stimulation in one direction produced significant response decrements in cumulative displacement,(More)
The dependence of human optokinetic afternystagmus (OKAN) velocity storage (charging) and optokinetic nystagmus (OKN) characteristics on optokinetic (OK) stimulus exposure time was investigated, using the two-component double exponential model for OKAN decay. Results are compatible with our previously proposed concept of two velocity storage integrators,(More)