David J. Hicks

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Diversity in temperate forests is concentrated in the understory, but understory dynamics are poorly understood for old-growth forests. We use repeated measurements of more than eight hundred 1 m2 plots over three decades to assess patterns of understory diversity in old-growth mesic and wet forests in northern Michigan, USA. We ask whether diversity(More)
The recent development of targeted therapies using monoclonal antibodies has added new dimensions to breast cancer treatment. Trastuzumab has been added to the regimens that contain chemotherapeutic agents, which has improved the clinical outcomes of patients in both the adjuvant and metastatic settings. However, trastuzumab resistance, both de novo and(More)
Transfection studies on DNA obtained from 16 multiple sclerosis (MS) and 13 non-MS brain tissues suggested that 3/16 (19%) MS and 3/13 (23%) non-MS samples contained contaminating measles virus double-stranded RNA, and that 6/16 (38%) MS and 0/13 non-MS samples contained DNA transcripts of measles genes. It is argued that the DNA transcripts most probably(More)
In the absence of spermatozoa, acid phosphatase activity (ACP) is an indicator of seminal fluid in cases of sexual assault. Both qualitative and quantitative ACP methods are employed by medical examiners. A large series of cases in which a qualitative test was employed is reported. A method for obtaining and handling specimens by vaginal washing was(More)
MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain(More)
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