David J. Deshazer

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Synchronization of the chaotic intensity fluctuations of three modulated Nd:YAG lasers oriented in a linear array with either a modulated pump or loss is investigated experimentally, numerically, and analytically. Experimentally, synchronization is only seen between the two outer lasers, with little synchrony between outer and inner lasers. Using a false(More)
The bacterial SOS response is a well-characterized regulatory network encoded by most prokaryotic bacterial species and is involved in DNA repair. In addition to nucleic acid repair, the SOS response is involved in pathogenicity, stress-induced mutagenesis, and the emergence and dissemination of antibiotic resistance. Using high-throughput sequencing(More)
Burkholderia mallei is an infectious intracellular pathogen whose virulence and resistance to antibiotics makes it a potential bioterrorism agent. Given its genetic origin as a commensal soil organism, it is equipped with an extensive and varied set of adapted mechanisms to cope with and modulate host-cell environments. One essential virulence mechanism(More)
Burkholderia mallei (Bm), the causative agent of the predominately equine disease glanders, is a genetically uniform species that is very closely related to the much more diverse species Burkholderia pseudomallei (Bp), an opportunistic human pathogen and the primary cause of melioidosis. To gain insight into the relative lack of genetic diversity within Bm,(More)
The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis Abstract Background: The Gram-negative bacterium Burkholderia(More)
Synchronization of the chaotic intensity uctuations of three modulated Nd:YAG lasers oriented in a linear array with either a modulated pump or loss is investigated experimentally, numerically and analytically. Experimentally , synchronization is only seen between the two outer lasers, with little synchrony between outer and inner lasers. Using a false(More)
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