David J. Clements

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H69AR is a multidrug-resistant small cell lung cancer cell line derived from a drug-sensitive cell line, H69, by selection in doxorubicin. It is cross-resistant to a wide variety of natural product-type antineoplastic agents but does not overexpress P-glycoprotein. In the present study, the levels of GSH and GSH-related enzymes in the H69AR cell line were(More)
The purpose of this paper is to provide an evaluation of the three open-source LP optimization codes, GLPK, COIN-LP (CLP) and LPSOLVE in solving electricity spot market optimization problems. The paper describes a technique for automatically generating over 100 locational marginal pricing (LMP) electricity spot market optimization problems, each being(More)
A solution X of a discrete-time algebraic Riccati equation is called unmixed if the corresponding closed-loop matrix Φ(X) has the property that the common roots of det (sI − Φ(X)) and det (I − sΦ(X) *) (if any) are on the unit circle. A necessary and sufficient condition is given for existence and uniqueness of an unmixed solution such that the eigenvalues(More)