David J. Clements

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A solution X of a discrete-time algebraic Riccati equation is called unmixed if the corresponding closed-loop matrix Φ(X) has the property that the common roots of det (sI−Φ(X)) and det (I− sΦ(X)∗) (if any) are on the unit circle. A necessary and sufficient condition is given for existence and uniqueness of an unmixed solution such that the eigenvalues of(More)
H69AR is a multidrug-resistant small cell lung cancer cell line derived from a drug-sensitive cell line, H69, by selection in doxorubicin. It is cross-resistant to a wide variety of natural product-type antineoplastic agents but does not overexpress P-glycoprotein. In the present study, the levels of GSH and GSH-related enzymes in the H69AR cell line were(More)
delta 9-Tetrahydrocannabinol (THC) exposure inhibits numerous immunologic functions of macrophages. The ability of THC-exposed macrophages to provide costimulatory signals to helper T cell hybridomas was investigated by induction of interleukin-2 secretion by T cells in response to immobilized monoclonal anti-CD3 antibody. Exogenous interleukin-1 did not(More)