David Ian Wimpenny

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Biological parameters, such as bone resorption and formation constants, are important variables to achieve optimised hard tissue scaffolds design. To help to understand the modelling process that occurs when a scaffold is implanted it is vital to understand the rather complex bone remodeling process prevalent in native bone. One approach to developing a(More)
One approach to developing a mathematical model that predicts osteoactivity both in bio-scaffolds, as well as the in bone tissue in vivo, is based on a bio-cybernetic vision of basic multicellular unit (BMU) action. In the case of the model presented in this paper, some of the loops of regulation have been modified to reflect the range of allosteric control(More)
To help to understand the modelling process that occurs when a scaffold is implanted it is vital to understand the rather complex bone remodelling process prevalent in native bone. We have formulated a mathematical model that predicts osteoactivity both in scaffolds, as well as in bone in vivo and could set a basis for the more detailed allosteric models.(More)
This paper describes the use of a non-contact structured light scanning technique, computer aided design (CAD) and additive manufacturing (AM) to produce a burns pressure therapy splint, also known as mask or conformer. Masks such as this are used in the treatment of hypertrophic scars resulting from burns injuries. The case study described here is of a(More)
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