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  • Ginette Tardif, David Hum, Jean-Pierre Pelletier, Nicolas Duval, Johanne Martel-Pelletier
  • Medicine
  • BMC musculoskeletal disorders
  • 2009 (First Published: 1 December 2009)
  • BackgroundMMP-13 and IGFBP-5 are important factors involved in osteoarthritis (OA). We investigated whether two highly predicted microRNAs (miRNAs), miR-140 and miR-27a, regulate these two genes inContinue Reading
    Objective To compare gene expression in normal and osteoarthritic (OA) human chondrocytes using microarray technology. Of the novel genes identified, we selected follistatin, a bone morphogeneticContinue Reading
  • Ginette Tardif, David Hum, J. Pelletier, Nicolas Duval, Johanne Martel-Pelletier
  • Medicine
  • 2009 (First Published: 1 September 2009)
  • Conclusions: Preliminary data of this study suggest that CS alone or in combination with GS is able to decrease significantly synovitis as measured by US. The decrease in synovitis after SYSADOAContinue Reading
  • Gladys Valverde-Franco, Jean-Pierre Pelletier, +5 authors Johanne Martel-Pelletier
  • Medicine
  • Arthritis and rheumatism
  • 2012 (First Published: 1 November 2012)
  • OBJECTIVE In vitro activation of the receptor EphB4 positively affects human osteoarthritis (OA) articular cell metabolism. However, the specific in vivo role of this ephrin receptor in OA remainsContinue Reading
  • Zhiyong Fan, Ginette Tardif, +7 authors Johanne Martel-Pelletier
  • Biology, Medicine
  • Arthritis and rheumatism
  • 2006 (First Published: 1 August 2006)
  • OBJECTIVE Matrix metalloprotease 13 (MMP-13) plays a major role in osteoarthritic (OA) processes. We previously identified the AG-rich element (AGRE) regulatory site (GAAAAGAAAAAG) in the proximalContinue Reading
  • Ginette Tardif, J P Pelletier, David Hum, Christelle Boileau, Nicolas Duval, Johanne Martel-Pelletier
  • Biology, Medicine
  • Annals of the rheumatic diseases
  • 2006 (First Published: 1 February 2006)
  • OBJECTIVE To investigate the distribution of the bone morphogenic protein (BMP) antagonist chordin in normal and osteoarthritic cartilage and synovial membranes, and its regulation in chondrocytesContinue Reading