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This paper reports on our experience with the implementation of the Real-time Specification for Java on the Ovm open source Java virtual machine. We describe the architecture and main design decisions involved in implementing real-time Java on Ovm. We present the first use of Real-time Java in avionics in the context of control software for a ScanEagle(More)
One of the most powerful features of the real-time specification for Java (RTSJ) is the new memory management model based on scoped memory areas. This model allows programmers to ensure timely reclamation of memory and predictable performance, at the cost of an unfamiliar programming model. We report on experience using and implementing scoped memory areas.(More)
Decorin is a member of the expanding group of widely distributed small leucine-rich proteoglycans that are expected to play important functions in tissue assembly. We report that mice harboring a targeted disruption of the decorin gene are viable but have fragile skin with markedly reduced tensile strength. Ultrastructural analysis revealed abnormal(More)
Embryonic growth occurs predominately by an increase in cell number; little is known about growth mechanisms later in development when fibrous tissues account for the bulk of adult vertebrate mass. We present a model for fibrous tissue growth based on 3D-electron microscopy of mouse tendon. We show that the number of collagen fibrils increases during(More)
Tendons are composed of longitudinally aligned collagen fibrils arranged in bundles with an undulating pattern, called crimp. The crimp structure is established during embryonic development and plays a vital role in the mechanical behaviour of tendon, acting as a shock-absorber during loading. However, the mechanism of crimp formation is unknown, partly(More)