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Low-Fat Dietary Pattern and Risk of Cardiovascular Disease: The Women's Health Initiative Randomized Controlled Dietary Modification Trial

• Barbara V Howard, Linda V. Van Horn, +44 authors Jane Morley Kotchen
• JAMA
• 2006

CONTEXT Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed. OBJECTIVE To test the hypothesis… (More)

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice.

• Elena Elstner, Christoph Müller, +7 authors H Phillip Koeffler
• Proceedings of the National Academy of Sciences…
• 1998

Induction of differentiation and apoptosis in cancer cells through ligands of nuclear hormone receptors (NHRs) is a novel and promising approach to cancer therapy. All-trans-retinoic acid (ATRA), an… (More)

Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trial.

• Maria V. Grau, John A. Baron, +4 authors David Heber
• Journal of the National Cancer Institute
• 2003

BACKGROUND Calcium and vitamin D both appear to have antineoplastic effects in the large bowel. Although these nutrients are inter-related metabolically in bone and in the normal intestine, their… (More)

Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro.

• Navindra P Seeram, Lynn S. Adams, +4 authors David Heber
• Journal of agricultural and food chemistry
• 2006

Berry fruits are widely consumed in our diet and have attracted much attention due to their potential human health benefits. Berries contain a diverse range of phytochemicals with biological… (More)

In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in…

• Navindra P Seeram, Lynn S. Adams, +4 authors David Heber
• The Journal of nutritional biochemistry
• 2005

Pomegranate (Punica granatum L.) fruits are widely consumed as juice (PJ). The potent antioxidant and anti-atherosclerotic activities of PJ are attributed to its polyphenols including punicalagin,… (More)

Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement.

• David Heber, Ian Yip, J. Michael Ashley, David A. Elashoff, Robert M. Elashoff, Vay Liang W. Go
• The American journal of clinical nutrition
• 1999

BACKGROUND We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the American Heart Association Step I… (More)

An Endocrine Society Clinical Practice Guideline Endocrine and Nutritional Management of the Post-Bariatric Surgery Patient:

• David Heber, Frank L Greenway, Lee M. Kaplan, Edward Livingston, Javier Salvador
• 2010

Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours.

• Navindra P Seeram, Susanne M Henning, Yanjun Zhang, Marc A. Suchard, Zhengguo Li, David Heber
• The Journal of nutrition
• 2006

Ellagitannins (ETs) from pomegranate juice (PJ) are reported to have numerous biological properties, but their absorption and metabolism in humans are poorly understood. To investigate the… (More)

Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial.

• Michael H. Davidson, Jonathan B Hauptman, +8 authors Steven B. Heymsfield
• JAMA
• 1999

CONTEXT Orlistat, a gastrointestinal lipase inhibitor that reduces dietary fat absorption by approximately 30%, may promote weight loss and reduce cardiovascular risk factors. OBJECTIVE To test the… (More)

Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.

• Lynn S. Adams, Navindra P Seeram, Bharat Bhushan Aggarwal, Yasunari Takada, Daniel Sand, David Heber
• Journal of agricultural and food chemistry
• 2006

Phytochemicals from fruits such as the pomegranate (Punica granatum L) may inhibit cancer cell proliferation and apoptosis through the modulation of cellular transcription factors and signaling… (More)

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