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Model-based vision is firmly established as a robust approach to recognizing and locating known rigid objects in the presence of noise, clutter, and occlusion. It is more problematic to apply model-based methods to images of objects whose appearance can vary, though a number of approaches based on the use of flexible templates have been proposed. The(More)
We report the draft genome of the black cottonwood tree, Populus trichocarpa. Integration of shotgun sequence assembly with genetic mapping enabled chromosome-scale reconstruction of the genome. More than 45,000 putative protein-coding genes were identified. Analysis of the assembled genome revealed a whole-genome duplication event; about 8000 pairs of(More)
A method for building flexible shape models is presented in which a shape is represented by a set of labelled points. The technique determines the statistics of the points over a collection of example shapes. The mean positions of the points give an average shape and a number of modes of variation are determined describing the main ways in which the example(More)
We have developed a trainable method of shape representation which can automatically capture the invariant properties of a class of shapes and provide a compact parametric description of variability. We have applied the method to a family of flexible ribbons (worms) and to heart shapes in echocardiograms. We show that in both cases a natural(More)
BACKGROUND Depression is a major individual and public-health burden throughout the world and is managed mainly in primary care. The most effective strategy to reduce this burden has been believed to be education of primary-care practitioners. We tested this assumption by assessing the effectiveness of an educational programme based on a clinical-practice(More)
BACKGROUND The continuing, randomised, multinational, phase IIB POWER 1 and 2 studies aim to evaluate efficacy and safety of darunavir in combination with low-dose ritonavir in treatment-experienced HIV-1-infected patients. We did a pooled subgroup analysis to update results at week 48 for patients receiving the recommended dose of darunavir-ritonavir(More)