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  • David Grimwade, Helen Mary Walker, +8 authors A H Goldstone
  • Medicine
  • Blood
  • 1998 (First Publication: 1 October 1998)
  • Cytogenetics is considered one of the most valuable prognostic determinants in acute myeloid leukemia (AML). However, many studies on which this assertion is based were limited by relatively smallExpand
  • David Grimwade, Helen Mary Walker, +6 authors Anthony H. Goldstone
  • Medicine
  • Blood
  • 2001 (First Publication: 1 September 2001)
  • Acute myeloid leukemia (AML) in older adults carries a poor prognosis, and the optimum treatment remains to be determined. In younger patients, treatment stratification is frequently based uponExpand
  • Timothy P Hughes, Michael Deininger, +18 authors John M. Goldman
  • Medicine
  • Blood
  • 2006 (First Publication: 1 July 2006)
  • The introduction in 1998 of imatinib mesylate (IM) revolutionized management of patients with chronic myeloid leukemia (CML) and the second generation of tyrosine kinase inhibitors may prove superiorExpand
  • Daniela Cilloni, Aline Renneville, +17 authors David Grimwade
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2009 (First Publication: 1 November 2009)
  • PURPOSE Risk stratification in acute myeloid leukemia (AML) is currently based on pretreatment characteristics. It remains to be established whether relapse risk can be better predicted throughExpand
  • Alan Kenneth Burnett, David Grimwade, E. Solomon, Keith Wheatley, Anthony H. Goldstone
  • Medicine
  • Blood
  • 1999 (First Publication: 15 June 1999)
  • All-trans retinoic acid (ATRA) is an essential component of the treatment of acute promyelocytic leukemia (APL), but the optimal timing and duration remain to be determined. MolecularExpand