David Glasser

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Hepatic function can be characterized by the activity/time curves obtained by imaging the aorta, spleen, and liver. Nonparametric deconvolution of the activity/time curves is clinically useful as a diagnostic tool in determining organ transit times and flow fractions. The use of this technique is limited, however, because of numerical and noise problems in(More)
Knowing which method parameters may be mutated during a method's executionis useful for many software engineering tasks. We present an approach todiscovering parameter reference immutability, in which several lightweight, scalable analyses are combined in stages, with each stage refining the overall result. The resulting analysis is scalable and combines(More)
BACKGROUND AND OBJECTIVE Because patients with diabetes mellitus may visit their primary care physician regularly but not their ophthalmologist, a retinal risk assessment in the primary care setting could improve the screening rate for diabetic retinopathy. An imaging system for use in the primary care setting to identify diabetic retinopathy requiring(More)
We use the attainable region (AR) technique to generate reactor network synthesis solutions to the WGS reaction system that is overall adiabatic. We first do this using the conventional method, as described by Nicol et al. (Comp. Chem. Eng. 21 (1001) 1997, s35), to generate the candidate AR (AR) for exothermic reversible reactions in three dimensions. We(More)
During extracorporeal procedures like hemodialysis, heparin is administered to patients to prevent clotting. Unfractionated heparin has side effects such as excessive bleeding. It would be advantageous if the blood could be deheparinased before it returns to the patient. Previous work has indicated that poly-L-lysine/alginate beads can efficiently remove(More)
cultures of mammalian cells as well as bacteria expressing other ABC transporters—have led most researchers to believe that P-gp operates by directly binding and transporting multiple types of substrate molecules out of cells (6) (see the figure, panel A). Nevertheless, controversy remains. Alternative models have been proposed in which P-gp alters a single(More)
Shortcut design techniques have been employed in the initial design of traditional distillation systems. Current techniques are not useful in the design of novel or complex configurations however. We will show that by using column profile mapping “moving triangles” to model the behaviour of column sections (CS), any distillation configuration, no matter how(More)
260 What is the minimum amount of carbon dioxide that a process can produce? This may seem like a trivial question but it is not a question usually asked when processes are being designed. In many cases, there is a lack of a quantitative description of what is the highest efficiency, least amount of energy, or lowest amount of carbon dioxide that can be(More)