David Gitlin

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The passage of plasma proteins from mother to fetus in humans appears to be highly selective. Although a number of antibodies such as those against diphtheria (1, 2) and tetanus toxins (3), typhoid H antigen (4), and poliomyelitis virus (5) readily cross from the maternal plasma to that of the fetus, other antibodies such as those against typhoid 0 antigen(More)
Seven of 10 patients with visceral larva migrans (VLM) had serum precipitating antibodies specific for larval antigens of Toxocara canis as determined by double diffusion in agar. Such antibodies were absent in 114 normal adults and 25 patients with collagen disease. Precipitation of ascarid components by C-reactive protein resulted in false-positive(More)
The analysis of specific proteins in single cells is described and applied to the determination of immunoglobulins G, A, and M (gammaG, gammaA, and gammaM) in lymphoid cells of the human tonsil. The number of cells containing gammaA or gammaM was much less than the number of cells containing gammaG, but the average cell content of gammaA or gammaM was much(More)
In individuals with similar body stores of iron, the amount of iron absorbed from a single oral dose is not proportional to the amount of iron administered. Although a greater amount of iron is absorbed as the size of the oral dose increases, the percentage or fraction of the dose that is absorbed actually decreases (1-3). In addition, the amount of iron(More)
The synthesis of gammaG, gammaA, gammaM, beta(1C)/beta(1A), C'1 esterase inhibitor, ceruloplasmin, transferrin, hemopexin, haptoglobin, fibrinogen, alpha(1)-antitrypsin, orosomucoid, beta-lipoprotein, alpha(2)-macroglobulin, and prealbumin was studied in 15 normal human embryos and fetuses of 29 days to 18 wk gestation and in the yolk sacs of four embryos(More)