Although evidence supports the use of double-blind placebo medication trials to evaluate methylphenidate (MPH) effects on the core behavioral symptoms of attention-deficit/hyperactivity disorder (ADHD), few studies have demonstrated their utility in examining MPH effects on the cognitive deficits associated with ADHD. This article presents a technique for… (More)
BACKGROUND Increasing evidence suggests that seizures and status epilepticus can be immune-mediated. We aimed to describe the clinical features of a new epileptic disorder, and to establish the target antigen and the effects of patients' antibodies on neuronal cultures. METHODS In this observational study, we selected serum and CSF samples for antigen… (More)
Previous experiments testing grating and vernier acuities in albino central vision are consistent with the hypothesis that the deficit in their monocular spatial processing is mainly due to the increased spacing of their foveal cones. This was tested by measuring albino spatial frequency discrimination over the range 0.25-4.0 cpd. The same experiments were… (More)
Intracranial hemorrhage accounts for about 50% of all pediatric stroke. Studies of term infants with intracranial hemorrhage have shown favorable motor and cognitive outcome. The goal of this study was to examine the risk of developing epilepsy in full-term infants with intracranial hemorrhage. A retrospective study was performed of term neonates (greater… (More)
Investigators from the University of California San Francisco and Kaiser Permanente Medical Centers in Oakland report outcome of perinatal arterial ischemic stroke (PAIS) in a population-based cohort, with particular attention to the incidence of seizures.
BACKGROUND Our aim was to determine whether early anatomical injury patterns on magnetic resonance imaging-correlate with the development of postneonatal epilepsy in infants treated with selective head cooling for hypoxic-ischemic encephalopathy. METHODS We retrospectively analyzed infants ≥35 weeks' gestation born between 2008 and 2013 and followed for… (More)