Learn More
Hematopoiesis is precisely orchestrated by lineage-specific DNA-binding proteins that regulate transcription in concert with coactivators and corepressors. Mutations in the zebrafish moonshine (mon) gene specifically disrupt both embryonic and adult hematopoiesis, resulting in severe red blood cell aplasia. We report that mon encodes the zebrafish ortholog(More)
Zebrafish genome sequencing project has improved efficiency of positional cloning in zebrafish and traditional chromosome walking by isolating large insert genomic libraries has become a past. However, the genetic principles underlying the positional cloning still form the foundation for current chromosome walking using the genome sequence assemblies and(More)
Integrins containing the alpha2 and alpha3 subunits associate with the beta1 subunit to form distinct receptors with partially overlapping adhesive specificities. We report the cloning and sequence of cDNAs that encode the Xenopus orthologues of integrins alpha2 and alpha3 and the expression of these subunits during embryogenesis. Integrin alpha2 and alpha3(More)
BACKGROUND Fish melanocytes aggregate or disperse their melanosomes in response to the level of intracellular cAMP. The role of cAMP is to regulate both melanosome travel along microtubules and their transfer between microtubules and actin. The factors that are downstream of cAMP and that directly modulate the motors responsible for melanosome transport are(More)
As subsea compression becomes a vital technology to the successful production of gas reserves in the North Sea, several technology issues will come to the forefront of the oil and gas industry. One of these important subjects is the capability to compress gas which includes a significant amount of liquids. Compressing wet gas requires knowledge in areas(More)
His professional experience over the last 10 years includes engineering and management responsibilities at Boeing, Turbocare, and Rocketdyne. Mr. Ransom's research interests include rotordynamics, structural dynamics, seals and bearings, finite element analysis, and root cause failure analysis. He has authored 12 technical papers in the field of(More)
Integrins containing the a2 and a3 subunits associate with the b1 subunit to form distinct receptors with partially overlapping adhesive specificities. We report the cloning and sequence of cDNAs that encode the Xenopus orthologues of integrins a2 and a3 and the expression of these subunits during embryogenesis. Integrin a2 and a3 mRNAs are first expressed(More)
  • 1