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Do body size components, such as weights of internal organs and long bone lengths, with different functions and different developmental histories also have different genetic architectures and pleiotropic patterns? We examine murine quantitative trait loci (QTL) for necropsy weight, four long bone lengths, and four organ weights in the LG/J × SM/J(More)
While the age-related loss in muscle mass partially explains the decline in strength, other yet undefined mechanisms contribute. This study investigates whether changes in myosin-actin stoichiometry and oxidative modification could help explain the decrement in muscle strength with aging. Protein expression and oxidation were evaluated in myosin and actin(More)
The MAPA system provides improved navigation facility for large web sites. It extracts a hierarchical structure from an arbitrary web site, with some minimal user assistance, and creates an interactive map of that site that can be used for orientation and navigation. MAPA is designed and most useful for large web sites of from 500 to 50,000 pages. We(More)
THE WAY IN WHICH TEXT IS represented on a computer affects the kinds of uses to which it can be put by its creator and by subsequent users. The electronic document model currently in use is impoverished and restrictive. The authors argue that text is best represented as an ordered hierarchy of content object (OHCO), because that is what text really is. This(More)
The aim of this study was to develop and analyze in vitro azithromycin (AZM)-resistant mutants of Escherichia coli and Shigella boydii. Three clinical isolates of E. coli and one S. boydii isolated from feces samples collected from children under 5 years of age with diarrhea in Lima, Peru were inoculated onto Mueller-Hinton plates containing increasing(More)
Web) standards provide simple support for applications that allow remote editing of typed data. In practice, the existing capabilities of the WWW have proven inadequate to support efficient, scalable, remote editing, free of overwrit-ing conflicts. A list of features in the form of requirements which, if implemented, would improve the efficiency of common(More)
UNLABELLED INTRODUCTION; Diarrheagenic E. coli (DEC) are a major cause of diarrhea in children in developing countries. However, they are not part of routine diagnosis in clinical laboratories. OBJECTIVES To determine the DEC prevalence in Peruvian children and to describe the genetic variability of these strains. MATERIALS AND METHODS A total of 8 003(More)