Learn More
The hepatitis C virus (HCV) persists in the majority of infected individuals and is a significant cause of human illness and death globally. Recent studies have yielded important insights into immunity to HCV, in particular revealing the central role of T cells in viral control and clearance. Other key features of adaptive immune responses remain obscure,(More)
The mechanisms by which the hepatitis C virus (HCV) establishes persistence are not yet fully understood. Previous chimpanzee and now human studies suggest that mutations within MHC class I–restricted HCV epitopes might contribute to viral escape from cytotoxic T lymphocyte (CTL) responses. However, there are several outstanding questions regarding the role(More)
EXECUTIVE SUMMARY INTRODUCTION Autonomous intelligent entities have been the focus of a substantial amount of research, both within Canada and internationally, over the last ten years. This report provides a high-level evaluation of the current state of the art of this technology in Canada. It also presents the technological barriers that must be overcome(More)
  • 1