David Floyd

Laxman Nallan1
Jay D Smith1
Kavit Amin1
Kasey Rivas1
Kohei Yokoyama1
1Laxman Nallan
1Jay D Smith
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New therapeutics to combat malaria are desperately needed. Here we show that the enzyme protein farnesyltransferase (PFT) from the malaria parasite Plasmodium falciparum (P. falciparum) is an ideal drug target. PFT inhibitors (PFTIs) are well tolerated in man, but are highly cytotoxic to P. falciparum. Because of their anticancer properties, PFTIs comprise(More)
We present an interesting method of shaping a vascularized medial femoral condyle (MFC) flap into a "neophalanx" for phalangeal reconstruction. Our patient presented with limited strength and function secondary to fracture nonunion of the proximal phalanx of the dominant thumb. Following excision of the pseudarthrosis, an MFC corticoperiosteal flap was(More)
Preoperative perforator marking for deep inferior epigastric artery perforator flaps is vital to the success of the procedure in breast reconstruction. Advances in imaging have facilitated accurate identification and preselection of potentially useful perforators. However, the reported imaging accuracy may be lost when preoperatively marking the patient,(More)
INTRODUCTION Two systems exist for describing fingers and phalanges: Naming and Numbering. This can cause confusion for clinicians. We compared the two systems to see if one was better understood. METHODS Thirty-eight clinicians were asked a questionnaire to identify 11 terms on hand outline drawings. RESULTS Naming was better understood than Numbering(More)
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