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Identification of the gene responsible for Best macular dystrophy

• Konstantin Petrukhin, Markus J. Koisti, +15 authors Claes Wadelius
• Nature Genetics
• 1998

Best macular dystrophy (BMD), also known as vitelliform macular dystrophy (VMD2; OMIM 153700), is an autosomal dominant form of macular degeneration characterized by an abnormal accumulation of… (More)

The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in…

• Gene G. Kinney, Cyrille Sur, +6 authors P Jeffrey Conn
• The Journal of neuroscience : the official…
• 2003

Glycine acts as a necessary coagonist for glutamate at the NMDA receptor (NMDAR) complex by binding to the strychnine-insensitive glycine-B binding site on the NR1 subunit. The fact that glycine is… (More)

Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception.

• Q Liu, Xiao-ming Guan, +14 authors Christopher P. Austin
• The Journal of biological chemistry
• 2001

The two mammalian neuropeptides NPFF and NPAF have been shown to have important roles in nociception, anxiety, learning and memory, and cardiovascular reflex. Two receptors (FF1 and FF2) have been… (More)

Ecological networks--beyond food webs.

• Thomas C. Ings, José Alfonso Monestel Montoya, +14 authors Guy Woodward
• The Journal of animal ecology
• 2009

1. A fundamental goal of ecological network research is to understand how the complexity observed in nature can persist and how this affects ecosystem functioning. This is essential for us to be able… (More)

A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy

• Kang Zhang, Marina Kniazeva, +17 authors Konstantin Petrukhin
• Nature Genetics
• 2001

Stargardt-like macular dystrophy (STGD3, MIM 600110) and autosomal dominant macular dystrophy (adMD) are inherited forms of macular degeneration characterized by decreased visual acuity, macular… (More)

N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient…

• Kevin S. Thorneloe, Anthony C. Sulpizio, +18 authors Timothy D. Westfall
• The Journal of pharmacology and experimental…
• 2008

The transient receptor potential (TRP) vanilloid 4 (TRPV4) member of the TRP superfamily has recently been implicated in numerous physiological processes. In this study, we describe a small molecule… (More)

Effect of El Niño and ambient temperature on hospital admissions for diarrhoeal diseases in Peruvian children.

• William Checkley, Leon D. Epstein, +4 authors R E Black
• Lancet
• 2000

INTRODUCTION To investigate whether the El Niño phenomenon and ambient temperature had an effect on the epidemiology of childhood diarrhoea, we analysed data on daily number of admissions of children… (More)

Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2.

• Robert N. Willette, Weike Bao, +21 authors Xiaoping Xu
• The Journal of pharmacology and experimental…
• 2008

The transient receptor potential (TRP) vanilloid subtype 4 (V4) is a nonselective cation channel that exhibits polymodal activation and is expressed in the endothelium, where it contributes to… (More)

Tracing dissolved organic matter (DOM) from land-based aquaculture systems in North Patagonian streams.

• Jorge Nimptsch, Stefan Wölfl, +8 authors Daniel Graeber
• The Science of the total environment
• 2015

Chile is the second largest producer of salmonids worldwide. The first step in the production of salmonids takes place in land-based aquacultures. However, the effects of the discharge from these… (More)

Receptor for motilin identified in the human gastrointestinal system.

• Scott D. Feighner, C. P. Tan, +18 authors Andrew Howard
• Science
• 1999

Motilin is a 22-amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract of humans and other species. It affects gastric motility by stimulating interdigestive antrum and… (More)

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