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  • David Fenard, Wes Yonemoto, Carlos M. C. de Noronha, Marielle Cavrois, Samuel A F Williams, Warner C. Greene
  • Biology, Medicine
  • Journal of immunology
  • 2005 (First Publication: 1 November 2005)
  • The HIV-1 protein Nef enhances viral pathogenicity and accelerates disease progression in vivo. Nef potentiates T cell activation by an unknown mechanism, probably by optimizing the intracellularContinue Reading
  • Marielle Cavrois, Jason Neidleman, Jason F Kreisberg, David Fenard, Christian Callebaut, Warner C. Greene
  • Biology, Medicine
  • Journal of virology
  • 2006 (First Publication: 15 February 2006)
  • The maturation of dendritic cells (DCs) is associated with a diminished ability to support human immunodeficiency virus (HIV) replication; however, the precise step in the HIV life cycle impaired byContinue Reading
  • Thomas Maurin, David Fenard, Gérard Lambeau, Alain Doglio
  • Biology, Medicine
  • Journal of molecular biology
  • 2007 (First Publication: 1 March 2007)
  • Secreted phospholipases A(2) (sPLA(2)s) represent a new class of human immunodeficiency virus (HIV) inhibitors that block the early steps of virus entry into cells. Here, we applied an in vitroContinue Reading
  • Oliver T. Keppler, Ina Allespach, Lismarie Schüller, David Fenard, Warner C. Greene, Oliver T. Fackler
  • Biology, Medicine
  • Journal of virology
  • 2005 (First Publication: 1 February 2005)
  • After infection with human immunodeficiency virus (HIV), progression toward immunodeficiency is governed by a complex interplay of viral and host determinants. The viral accessory protein Nef is aContinue Reading
  • Virna Marin, Stefano Corna, +7 authors Chiara Bovolenta
  • Biology
  • 2015 (First Publication: 1 May 2015)
  • Cell therapy with T cells genetically modified with lentiviral vectors (LVs) carrying therapeutic genes is growing as a promising tool for tumor treatment. Noticeably, the clinical production ofContinue Reading
  • S. Barcellini-Couget, David Fenard, Edouard Bertrand, Robert H Singer, J. C. Lefèbvre, Alain Doglio
  • Biology, Medicine
  • Antisense & nucleic acid drug development
  • 1998 (First Publication: 1 October 1998)
  • Polymerase III (pol III)-dependent genes, like the adenoviral VA1 gene, are of particular interest for expressing small therapeutic RNAs into cells. A new VA1 RNA carrier molecule was generatedContinue Reading