David E. Uehling

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Blood vessels are formed through vasculogenesis, followed by remodeling of the endothelial network through angiogenesis. Many events that occur during embryonic vascular development are recapitulated during adult neoangiogenesis, which is critical to tumor growth and metastasis. Current antiangiogenic tumor therapies, based largely on targeting the vascular(More)
A double antibody method for quantitation of urinary immunoglobulins that is sensitive enough to avoid the need for urine concentrations has been developed. The first antibody is goat antiserum monospecific for the heavy chains of IgA, IgG, and IgM. The second, and precipitating, antibody is developed in rabbits made tolerant to human IgG. Normal values for(More)
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