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  • Mamoru Komatsu, Takuma Uchiyama, Satoshi Ōmura, David E Cane, Haruo Ikeda
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2010 (First Publication: 9 February 2010)
  • To construct a versatile model host for heterologous expression of genes encoding secondary metabolite biosynthesis, the genome of the industrial microorganism Streptomyces avermitilis wasContinue Reading
  • Steven Giglio, Jiaoyang Jiang, Christopher P. Saint, David E Cane, Paul T. Monis
  • Biology, Medicine
  • Environmental science & technology
  • 2008 (First Publication: 1 November 2008)
  • Geosmin is a secondary metabolite responsible for earthy tastes and odors in potable water supplies. Geosmin continues to be a challenge to water utility management regimes and remains one of theContinue Reading
  • Michael J Rynkiewicz, David E Cane, David W Christianson
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2001 (First Publication: 20 November 2001)
  • The x-ray crystal structure of recombinant trichodiene synthase from Fusarium sporotrichioides has been determined to 2.5-A resolution, both unliganded and complexed with inorganic pyrophosphate.Continue Reading